I stumbled across this post on tumblr and I loved the various column widths. It allowed for captions, introductory paragraphs and the main body text to be flawlessly displayed in a visual hierarchy that works in an harmonious way.
The way the white space embraces the small text that is the captions lets the reader know that they accompany the image. The text boxes that spread over 2 columns must be more important and should be read first. This comes before devices such as a heavier weight of text, or taking advantage of the viewer reading top to bottom, left to right.